If your dose is different, do not change it unless your doctor tells you to do so. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.

• As such, it is advised to consider alternative medications for insomnia or other sleep disorders, as there are several medications available that cause fewer adverse effects 6.
• Seroquel can increase your blood sugar level, which can lead to diabetes.
• Take this medicine exactly as directed by your doctor to benefit your condition as much as possible.
• Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.
• The dosage may be increased at a slower rate, and a lower total daily dose may be used to lessen the risk of side effects.

Dose Dependency of Adverse Reactions in Short-Term, Placebo-Controlled Trials

If you experience any severe side effects, it’s essential to contact your healthcare provider immediately. Do not stop using Seroquel XR suddenly, your condition may get worse, or you could have unpleasant symptoms (such as trouble sleeping, nausea and vomiting). Seroquel XR is used to treat schizophrenia in adults and children who are at least 13 years old. Talk to your doctor about other drug options that may work for you. It hasn’t been confirmed that quetiapine is safe and effective to use for this purpose in children younger than 18 years. It hasn’t been confirmed that quetiapine is safe and effective to use for this purpose in children younger than 10 years.

Secondary Benefits of Seroquel Tablet

• Mammary gland adenocarcinomas were statistically significantly increased in female rats at all doses tested (0.3, 1, and 3 times the MRHD based on mg/m2 body surface area).
• It is, however, often administered off-label as a short-term sleep aid due to its sedative effects.
• If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away.
• Patients should be advised that elevations in total cholesterol, LDL-cholesterol and triglycerides and decreases in HDL-cholesterol may occur.
• In two clinical trials with SEROQUEL, one in bipolar mania and one in schizophrenia, reported increases in weight are included in Table 7.

Do not suddenly stop taking this medicine without checking first with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This will decrease the chance of having withdrawal symptoms such as nausea, vomiting, insomnia, dizziness, irritability, or headache. Your doctor may need to check your weight on a regular basis while you are using this medicine. This medicine may cause tardive dyskinesia (a movement disorder).

Report any unusual thoughts or behaviors that trouble you, especially if they are new or are getting worse quickly. Make sure the doctor knows if you have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell the doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Let the doctor know if you or anyone in your family has bipolar disorder (manic-depressive illness) or has tried to commit suicide.

Commonly Observed Adverse Reactions in Short-Term, Placebo-Controlled Trials

Quetiapine caused a dose-related reduction in plasma cholesterol levels in repeat-dose dog and monkey studies; however, there was no correlation between plasma cholesterol and the presence of cataracts in individual dogs. The appearance of delta-8cholestanol in plasma is consistent with inhibition of a late stage in cholesterol biosynthesis in these species. There also was a 25% reduction in cholesterol content of the outer cortex of the lens observed in a special study in quetiapine treated female dogs. The safety and effectiveness of SEROQUEL in the maintenance treatment of bipolar disorder has not been established in pediatric patients less than 18 years of age. The safety and effectiveness of SEROQUEL in the maintenance treatment of schizophrenia has not been established in any patient population, including pediatric patients.

Quetiapine may interact with other medications

You can also schedule a telemedicine appointment with one of our providers to discuss your treatment plan. Safety and effectiveness of SEROQUEL in pediatric patients less than 18 years of age with bipolar depression have not been established. A clinical trial with SEROQUEL XR was conducted in children and adolescents (10-17 years of age) with bipolar depression, efficacy was not established.

Antipsychotic treatment, itself, however, may suppress (or partially suppress) the signs and symptoms of the syndrome and thereby may possibly mask the underlying process. The effect that symptomatic suppression has upon the long-term course of the syndrome is unknown. There were suicides in the adult trials, but the number was not sufficient to reach any conclusion about drug effect on suicide. There have been literature reports suggesting false positive results in urine enzyme immunoassays for methadone and tricyclic antidepressants in patients who have taken quetiapine. Caution should be exercised in the interpretation of positive urine drug screen results for these drugs, and confirmation by alternative analytical technique (e.g., chromatographic methods) should be considered. Adverse reactions that were potentially dose-related with higher frequency in the 600 mg group compared to the 400 mg group included somnolence (50% vs. 57%), nausea (6% vs. 10%), and tachycardia (6% vs. 9%).

Seroquel XR

It has not been confirmed that quetiapine is safe and effective to use for this purpose in children younger than 13 years. We recognize the realities of mental health challenges and respond with compassion, connection, and community. Whether by providing reliable resources or helping you connect with the right therapist, you are always welcome as a valued member of our community. Always discuss your medications with your doctor before starting a new treatment. It’s not known whether it’s safe to take Seroquel while breastfeeding.

Clinical Study Experience

The side effects for this drug vary slightly based on the drug form. However, it’s thought that it helps regulate the amount of certain chemicals (dopamine and serotonin) in your brain to control your condition. MentalHealth.com is a health technology company guiding people towards self-understanding and connection. The platform provides reliable resources, accessible services, quetiapine seroquel: uses side effects and nurturing communities.

Warnings & Precautions

In the 26-week open-label clinical trial, one child with a reported history of hypertension experienced a hypertensive crisis. Blood pressure in children and adolescents should be measured at the beginning of, and periodically during treatment. Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Analysis of 17 placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. Over the course of a typical 10-week controlled trial, the rate of death in drug-treated patients was about 4.5%, compared to a rate of about 2.6% in the placebo group. Although the causes of death were varied, most of the deaths appeared to be either cardiovascular (e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature.